Utskrift från Malmö universitets webbplats www.mah.se

Detection of tumor biomarkers based on MIP-antibody proximity ligation assays and fluorescent synthetic nanoprobes

Contact person: Celina Wierzbicka
Responsible: Celina Wierzbicka
Co-workers: Börje Sellergren, Anette Gjörloff Wingren and Tautgirdas Ruzgas
Partner: ImaGene-iT AB, Phase Holographic Imaging AB, Uppsala University, Umeå University
Funding: KK-stiftelsen
Timeframe: 2017-09-01 -- 2019-08-31
Forskningscentrum: Biofilms - Research Center for Biointerfaces
Faculty/Department: Faculty of Health and Society, The Department of Biomedical Science
Subject: Naturvetenskap

The aim of this project is to develop glycan specific probes in the form of fluorescent or DNA-modified molecularly imprinted polymer (MIP) nanoparticles for use in clinically relevant cancer diagnostics technologies. The synthetic probes will be used alone or in combination with antibodies in novel MIP-antibody proximity ligation assays for detection of soluble or cell surface biomarkers using state of the art imaging technologies. The proposal is a joint project of Malmö University, Umeå University, Uppsala University and two companies: ImaGene-iT and Phase Holographic Imaging AB. 

Senast uppdaterad av Magnus Jando