Utskrift från Malmö universitets webbplats www.mah.se

Biological Responses to Self Assemblying Calcium Phosphates

Contact person: Ryo Jimbo
Responsible: Ryo Jimbo
Co-workers: Ann Wennerberg
Partner: Martin Andersson, Chalmers Tekniska Högskola, Göteborg, Kamal Mustafa, Bergen Universitet, Bergen, Norge, Humberto Ozvaldo Schwartz-Filho, São Paulo State University, Araraquara, Brazil
Funding: Swedish Research Council and Hjalmar Svensson Research Foundation
Timeframe: 2011-03-01 -- 2013-02-28
Research profile: Oral hälsa
Faculty/Department: Faculty of Odontology

In the past, the prerequisite for biomaterials were that they should be ‘bioinert’. However, recent studies indicate that ‘bioactive’ materials may further increase its biocompatibility. Naturally, the so-called ‘biomimetic engineering’ concept has been the trend in the field of implant dentistry. In this project, we propose a novel implant surface, which will self assemble and transform during the bone healing period. In a preliminary study, we have confirmed that this unique nano-structured calcium phosphate material will self assemble when it is in contact with blood, and both the structure and calcium ratio successfully mimicked actual living bone. Both in vitro and in vivo studies will be conducted to determine the biological effects as a result of the novel surface modification.

Senast uppdaterad av Catarina Christiansson