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Recurrent Aphthous Stomatitis

The Greek term aphthai was initially used in relation to disorders of the mouth and is credited to Hippocrates ( 460-370 BC ). Today, recurrent aphthous ulceration or stomatitis (RAS), is recognized as the most common muc osal disease known to human beings.

Epidemiological studies indicate that the prevalence of RAS is between 2% and 50% in the general population, most estimates fall between 5% and 25%. The age of onset for RAS is 10- 19 years. After childhood and adolescence, it may continue thr oughout the entire life without geographic or age-, sex- or race-related preference.


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Possible causes

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Differential diagnosis

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Clinical pictures

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Source: Ship AJ, Chavez EM, Doerr PA, Bradley SH and Sarmadi M. Recurrent aphthous stomatitis, Quintessence Int, 2000; 31 : 95-112

* Our thanks to Dr. Tony Axéll for giving us permission to use material from this source: Axéll T. En Encyklopedi om Munslemhinneförändringar. Swedish/English version, CD-Rom, Version 1.0, Gothia, Stockholm, 1997.

Last updated by Marie Nordström