Utskrift från Malmö högskolas webbplats www.mah.se

Smart materials at interfaces

Artficial biomimicry

Biomimicry (defined as the imitation of life or nature) is used in biomedicine and biotechnology to develop novel treatments and diagnostic methods. We have two major focuses in the biomimicry area; a) development of novel diagnostic tools for cancer and b) biomimetic systems for better understanding of the onset and treatment of various diseases including atherosclerosis and bacterial infections.

To find new and better ways to diagnose and treat cancer is one of the most pressing tasks for researchers today. Early diagnosis where the cancer is still curable is therefore crucial. This emphasizes the need for sensitive, robust and affordable diagnostic tools that can sense the cellular state, commonly in the form of tumor specific protein markers, early in the process. We are developing and using molecularly imprinted polymers or “plastic antibodies” and other smart materials to detect and sense previously inaccessible tumor markers and to discover novel disease biomarkers. 

Biosensors and implantable bioelectronics

Research on Biosensors and Implantable Bioelectronics is focused on development of specific analytical devices and methods for monitoring of clinically relevant analytes and biomarkers, as well as development of potentially implantable electric power devices. It includes synthesis and characterization of nanomaterials, development of novel sensing and power generating principles, as well as assessment of biosensor and biofuel cell performance in clinical and implantable situations. Our strongest experience is in electrochemical sensors and enzymatic fuel cells. Lately, we have exploited biosensor approaches for the investigation of processes at biological barrier, tested enzymatic fuel cells in human blood under homeostatic conditions, as well as disclosed a new type of bioelectronics devices – self-charging biosupercapacitors.

Mathematical modeling

Scientific computing and simulations of phenomena on micro- and macroscopic scale is a field of great importance in modern science. General mathematical techniques, such as differential equations, combined with computational methods allow a very broad range of applications. Our main focus is on three different areas; computational quantum physics, modeling of infectious diseases and resonance spectrum for stratified media.

Ongoing projects

 

Biofuel Cells: From Fundamentals to Application in Bioelectrochemistry

Detection and imaging of circulating tumour cells – a novel approach using nanoprobes and microscopy as diagnostic tools

Diagnostic tools for neurodegenerative disease biomarkers based on robust optically signaling capture phases

GlycoImaging

Lipoprotein structure in the bulk and at the surface of vessel wall components

MIP4CELL

Non-invasive multi-parameter biomedical devices: Disclosing hidden fitness and health indicators

Restorable and adaptable surfaces for molecular recognition, biosensing and evanescent microscopy of human cells

Screening of different surface coatings on titanium including different API´s for enhanced wound healing

Self-charging biosupercapacitor

Silica-based nanoporous microparticles for controlled release applications and development of creative materials

Surface modification with natural as well as artifical active substances of dental materials with the aim to promote and keep good health for the spare part human

The BioCapture Network - Smart Capture Phases for Proteomics, Glycomics and Biomarker Assays

Wireless electronics powered by nanostructured, flexible, and transparent biofuel cells

Last updated by Magdalena Almén